About Us

CustomArray, Inc. is a provider of oligo pools to many of the world's leading academic and industrial organizations for applications including targeted sequencing, complex DNA libraries, synthetic biology, shRNA libraries, CRISPR, etc.  See example publications below that used our oligo pools, including review of applications by Kosuri and Church. 

We synthesize DNA electrochemically on arrays of electrodes and then cleave the DNA off to create oligo pools.  We have two platforms:  arrays with 12,000 electrodes (allowing creation of 12,000 different oligos per array) and arrays with 90,000 electrodes (allowing creation of 90,000 different oligos per array).  The advantage of this process is that it can produce libraries of DNA at extremely low price per base (as low as 0.04 cents per base -- see pricing here).

Improvements over the past nearly two decades now allow us to create up to 200 mers with average error rates typically around 1 error per 150 bases to 1 per 200 bases.

We also sell DNA arrays and related products suitable for the usual assortment of DNA-array applications (gene expression, genotyping, etc.), including an inexpensive, accurate, hand-held-sized DNA-array reader.

Example Publications

"Large-scale de novo DNA synthesis: technologies and applications," by Sriram Kosuri and George M. Church, Nature Methods, May, 2014, Vol. 11, No. 5, pp. 499–507.

"Genetic Screens in Human Cells Using the CRISPR/Cas9 System," by Tim Wang, Jenny J. Wei, David M. Sabatini, and Eric S. Lander, Science, Jan. 3, 2014, Vol. 343, no. 6166, pp. 80-84.

"Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells", by Ophir Shalem, Neville E. Sanjana, Ella Hartenian, Xi Shi, David A. Scott, Tarjei Mikkelson, Dirk Heckl, Benjamin L. Ebert, David E. Root, John G. Doench, Feng Zhang, Science, 3 January 2014, Vol. 343, no. 6166, pp. 84-87.

"Robust Chemical Preservation of Digital Information on DNA in Silica with Error-Correcting Codes," by Grass, R. N., Heckel, R., Puddu, M., Paunescu, D. and Stark, W. J. (2015). Angew. Chem. Int. Ed., 54: 2552–2555.